Azathioprine side-effects: What should I do if I experience this? Before using Azathioprine Tablet, inform your doctor about your current list of medications, over the counter products (e.g. These blood tests will ensure that any concerns or problems are found quickly. However, both azathioprine and alcohol can affect your liver. Commonly reported side effects of azathioprine include: infection, nausea, leukopenia, and vomiting. There are several different treatments that can help the symptoms of inflammatory conditions. Advertising revenue supports our not-for-profit mission. 4.2 Posology and method of administration . All rights reserved. Do not drink too much alcohol. These include medicines, other types of therapy and even surgery. Mayo Clinic does not endorse companies or products. If you take it after a transplant you will not notice any benefits from the medicine itself.  Warfarin and acenocoumarol: Azathioprine inhibits the anticoagulant effects of coumarins. Azathioprine is a type of medicine called an immunosuppressant. Generally IBD patients are not offered thiopurines when first diagnosed, only after they have achieved remission on other treatments. No Yes . Generally IBD patients are not offered thiopurines when first diagnosed, only after they have achieved remission on other treatments. Azathioprine is not a painkiller, but as a result of reducing the inflammation caused by conditions such as rheumatoid arthritis, you may have less pain. It is important to tell them that you took azathioprine during pregnancy. It is used to treat disorders in dogs such as hemolytic anemia, thrombocytopenia, some chronic liver, kidney, and stomach / intestinal diseases, and arthritis and skin diseases caused by a immune-mediated issue. If you forget doses often, it may help to set an alarm to remind you. However, it takes a while for azathioprine to work. You could be having a serious allergic reaction and may need immediate treatment in hospital. Ask a pharmacist to recommend a painkiller. This is not a complete list of side effects and others may occur. They will tell you if you need to stop treatment until these symptoms get better. More common side effects. They’ll review your treatment and tell you if it’s OK to keep taking azathioprine. Tell your doctor before taking this medicine if you: Always follow your doctor's instructions for how to take azathioprine. Contents of the pack and other information Use of Azathioprine in renal transplant patients may lead to an increase in 1. Vasculitis UK recommends the following website for information about cortisone (steroids) ... Azathioprine (Imuran) An important and very commonly used immunosuppressant. Call your doctor for medical advice about side effects. information for parents and carers These side effects are more likely when you first start taking azathioprine or when your dose is increased. What are the possible side effects? Mercaptopurine is used less often than azathioprine in the UK. Chipper03 • • 4 Replies. Small amounts of azathioprine may pass into your breast milk. We will also be monitoring the amount of active azathioprine in your blood, using a blood test called thioguanine nucleotides levels (TGNs).  Rarely, patients may be allergic to azathioprine. It is also available as an injection, but this is usually only given in hospital. Residues should be disposed of with the same caution. vitamins, herbal supplements, etc. Check with your doctor or a pharmacist if you miss 2 doses or more. Nausea and vomiting are common adverse effects, especially at the beginning of a treatment. I tried 100mg and was vomiting all the time. From day 2 onwards, you'll take 1mg to 4mg for each kilogram you weigh. This content does not have an Arabic version. Azathioprine can be very effective in providing remission from the symptoms caused by inflammatory bowel disease, and in allowing smaller doses of steroids to be used effectively whilst reducing the risk of relapse and steroid induced side effects. Home; About; Posts ; Members; Azathioprine side effects . when I tried to before my bloods showed problems and I had to raise steroid dosage again. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Upset stomach or throwing up. If you are vomiting or have severe diarrhoea for more than 24 hours, your contraceptive pills may not protect you from pregnancy. For this reason, you will need to keep taking your medicine if you have an autoimmune condition or have had an organ transplant. Our Imuran (azathioprine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Read more about what to do if you're on the pill and you're being sick or have diarrhoea. I started azathioprine 6 weeks ago for Vasculitis too and agree that with Jane that it makes me feel so much better. Other medicines can also affect the way azathioprine works. Side-effects, further information Side-effects may require drug withdrawal. Use a sunscreen while taking azathioprine, as this medicine can make your skin more sensitive to sunlight. Here is the some steps to help you to save money on Azathioprine purchase. If you develop any coronavirus symptoms, talk to your specialist doctor urgently. Speak to your doctor if you're worried about any of this. Continue to give azathioprine to your child as your doctor has told you to. Your doctor may lower your dose as your condition gets better. This may result in a … Further advice 5. 1. They will usually settle down within a week or so as their body gets used to the medicine. For inflammatory conditions such as rheumatoid arthritis and Crohn's disease, it can take up to 12 weeks of taking the "right" adjusted dose before you notice any benefits. Most adults and children can take azathioprine. headaches – make sure you rest and drink plenty of fluids. take ciclosporin or tacrolimus (immunosuppressant medicines), are having chemotherapy (used to treat cancer), are going to have any type of surgery – tell your doctor or anaesthetist that you take azathioprine beforehand, complementary therapies, including acupuncture, surgery to remove an inflamed section of bowel, a liquid diet (enteral nutrition), suitable for children and young adults. have had an allergic reaction to azathioprine or any other medicines (including mercaptopurine, a medicine for treating blood cancer), have an infection or a high temperature, or generally feel unwell, have a condition that affects your bone marrow, are due to have surgery involving muscle relaxants, have Lesch Nyhan syndrome, or a rare inherited condition affecting your NUDT15 gene, have ever been told that your body produces too little thiopurine methyltransferase (TMT, an enzyme), you take more than your prescribed dose of azathioprine (even if you feel well), you take too much azathioprine and feel unwell, you feel tired all the time, dizzy or sick, or you are vomiting or have diarrhoea, you have a high temperature with shivering or chills, cough or a sore throat, you get a rash or notice any changes to your skin, such as blisters or peeling, your pee changes colour or you start peeing more or less than usual (this can be a sign of kidney problems), you feel confused, lightheaded or weak (these can be signs of, you're bleeding or bruising more easily than usual, you have severe stomach ache (abdominal pain) and back pain, you get a skin rash that may include itchy, red, swollen, blistered or peeling skin, your mouth, face, lips, tongue or throat start swelling. vitamins, herbal supplements, etc. 4. For this reason, your doctor will prescribe the lowest level of therapy or lowest dose of medicine that works for you. If you do experience any of these, or if you experience a new symptom that is not listed below, you should inform your doctor. However, if you do have severe side effects, or are concerned about your symptoms, contact one of the healthcare professionals in charge of your care. You may report side effects to FDA at 1-800-FDA-1088. Discuss any questions or concerns with your doctor. As long as you have no symptoms of coronavirus infection, carry on taking your prescribed immunosuppressant medicine as usual. Azathioprine is available as 25 mg and 50 mg tablets. However if your doctor or health visitor says your baby is healthy, then it’s OK to take azathioprine when breastfeeding. Azathioprine 50 mg Tablets - Patient Information Leaflet (PIL) by Accord-UK Ltd Azathioprine side-effects: What should I do if I experience this? It can also lower the number of platelets, which are necessary for proper blood clotting. As azathioprine affects your immune system, it means that after your baby is born, there’s a very small risk it can affect the way they fight infections. Some people can feel weak, dizzy or lightheaded when taking azathioprine. This is not a complete list of side effects and others may occur. Hypersensitivity reactions Hypersensitivity reactions (including malaise, dizziness, vomiting, diarrhoea, fever, rigors, myalgia, arthralgia, rash, hypotension and renal dysfunction) call for immediate withdrawal. Azathioprine is used in the treatment of pemphigus and rheumatoid arthritis where it has significant therapeutic activity when used without corticosteroids. As with any medication there are potential side effects of taking azathioprine. Other side-effects you need to know about. For this reason it is even more important to stick to the national guidelines of drinking no more than 14 units a week for men and women. it may be prescribed as well as prednisolone as a steroid-sparing agent when your condition has flared up. Can taking azathioprine cause any side effects? Name: Azathioprine Shared Care Guideline Page 4 of 5 Version: 1.3 Issue Date: June 2013 Review Date: June 2015 Disease & drug monitoring: As above –contact GP or initiating team if side effects develop (see adverse effects) and attend appointments including those for routine blood If you notice that your baby isn't feeding as well as usual, or if you have any other concerns about your baby, talk to your health visitor, midwife or doctor as soon as possible. However, there is no strong evidence that it can harm your baby. What are the possible side effects of azathioprine? Azathioprine oral tablet doesn’t cause drowsiness, but it can cause other side effects. Can Taking Azathioprine Cause Any Side Effects? However, speak to your doctor if you are pregnant or trying for a baby. Menu People with normal thiopurine methyltransferase levels (see ‘Who should NOT take azathioprine’, below) can take azathioprine as a single dose, but if side effects such as sickness occur, dividing the dose and taking this medication twice a day may help. For more information about how azathioprine can affect you and your baby during pregnancy, read this leaflet on the best use of medicines in pregnancy (BUMPs) website. This leaflet provides information on a medicine called azathioprine when it is used to treat myasthenia gravis. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Lower doses of azathioprine are used as a therapy in children with refractory or corticosteroid-dependent Crohn's disease, without causing many side effects. It’s important for you to stay healthy while you are pregnant. hi Christina I was on azathioprine for about 3 years I didn't have any problems caused by it but was changed to mycophenolate as consultant said it would be easier to lower steroid on this without as many side effects. A certain severe condition called progressive multifocal leukoencephalopathy (PML) has been reported with use of Azathioprin AL. However there are some rare, but serious side effects that you would need to tell your doctor about immediately. Some patients who cannot tolerate azathioprine (due to side effects) may still be able to take mercaptopurine. A pint of lager or beer is 2 to 3 units of alcohol. This audit was a retrospective case note review of patients attending After reading this leaflet you should have an idea about what to expect if you start taking azathioprine, for example, how well it works, and what side-effects you may experience. From week 9 onwards you will have blood tests less often. For this reason, avoid strong sunlight and use a sunscreen (SPF 30 or more), and wear clothes that cover your arms and legs. It is not one of the standard disease modifying drugs used in the UK. This medicine is not suitable for some people. Your doctor will be able to recommend the best treatment for you, based on your condition and your symptoms. If at any point you develop these stop the drug and contact your doctor as soon as possible. For a full list, see the leaflet inside your medicine packet. Azathioprine or mercaptopurine are considered as treatment options You will have regular blood tests while taking azathioprine. What are the common side effects? PML is often fatal. Major side effects are unusual but blood tests must be monitored frequently when it is started or the dose is increased because there is a risk of liver toxicity and bone marrow suppression (low white cell count and … sheet does not list all of the side effects of azathioprine. If at any point you develop these stop the drug and contact your doctor as soon as possible. Side-effects may require drug withdrawal. Azathioprine uses and side effects Home : Azathioprine. Introduction . Azathioprine works by suppressing your immune system and therefore you may be more likely to get an infection. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. After a transplant, your body will try to attack the new organ as it sees it as "foreign". Azathioprine is available as 25 mg and 50 mg tablets. Everyone responds differently to the medication but possible side effects include: nausea, especially at the start of treatment. Look on the pill packet to find out what to do. Leaving aside the side effects, the positive side is that I have so much more energy. Azathioprine does not affect any type of contraception, including the combined pill and emergency contraception. Feeling extremely tired or dizzy, being sick (vomiting), loose or watery stools (diarrhoea), a high temperature (fever), muscle pain or stiffness, skin rash, kidney problems (such as a change in the amount or colour of your urine) These may be signs of an allergic reaction. Azathioprine is an immunosuppressant medicine used to stop your immune system from attacking parts of your body - get trusted advice on its uses and possible side effects. See below for less common side-effects. 6. During the early weeks of treatment, azathioprine may cause the following side effects: General feeling of being unwell including dizziness and generalised aches and pains. This causes severe ‘flu’-like symptoms (severe aches and pains, high fever and shaking). Side effects that are probably hypersensitivity reactions include dizziness, diarrhea, fatigue, and skin rashes. There are other potential side effects of Azathioprine which I have listed below: Common side-effects: nausea, vomiting, loss of appetite, low white blood cell counts, infection . Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. This causes severe ‘flu’-like symptoms (severe aches and pains, high fever and shaking). side effects: • General feeling of being unwell including dizziness and generalised aches and pains. In patients who are experiencing such side-effects, the aim of azathioprine treatment is to reduce the required maintenance dose of steroids. Your doctor will decide how often you need them. Azathioprine may cause: • feeling sick (nausea) • vomiting • diarrhoea • loss of appetite • hair loss • skin rashes • sensitivity to sunlight. See below for a comprehensive list of adverse effects. Most patients experience no problems with azathioprine. It has been taken by many breastfeeding mothers without any problems and extra monitoring is not usually required. Call your doctor for medical advice about side effects. azathioprine metabolism. Azathioprine has been reported to cause blood disorders, leading to weakness or breathlessness, an increased chance of infections (sore throat, fever, malaise), and a tendency to bleed/bruise easily. • Hair loss, although hair often does grow again, even if you carry on taking azathioprine. You may report side effects to FDA at 1-800-FDA-1088. A standard glass of wine (175ml) is 2 units of alcohol. Did you experience any side effects after consuming the medication? All medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. You may not experience any of these side effects listed. Find patient medical information for Azathioprine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. This means your immune system becomes weaker. • Stomach upsets such as loss of appetite, feeling or being sick and diarrhoea. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. You'll usually take your tablets once or twice a day. This site complies with the HONcode standard for trustworthy health information: verify here. Reported side effects include: An increased risk of infections. You could also ask a pharmacist for advice on other ways to help you remember to take your medicine. Mechanism of action. Unless you have severe side effects, it is important If your baby is unwell, speak to a doctor, your midwife or health visitor and ask for advice. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter, sores, ulcers, or white spots on the lips or in the mouth, greatly decreased frequency of urination or amount of urine, pains in the stomach, side, or abdomen, possibly radiating to the back, unusual feeling of discomfort or illness (sudden). It comes as tablets. Feeling extremely tired or dizzy, being sick (vomiting), loose or watery stools (diarrhoea), a high temperature (fever), muscle pain or stiffness, skin rash, kidney problems (such as a change in the amount or colour of your urine) These may be signs of an allergic reaction. 6,615 members • 5,812 posts. Discuss … In some patients, azathioprine can cause a feeling of sickness, diarrhoea, loss of appetite, hair loss and skin rashes. Taking azathioprine with food can help reduce sickness. There's very little information about taking herbal remedies and supplements with azathioprine. Taking azathioprine can affect the blood count (one of the effects is that fewer blood cells are made). Stop taking your medicine and contact your specialist or a doctor immediately if: In rare cases, it's possible to have a serious allergic reaction (anaphylaxis) to azathioprine. Before using Azathioprine Tablet, inform your doctor about your current list of medications, over the counter products (e.g. Vasculitis UK. Along with its needed effects, a medicine may cause some unwanted effects. Pricing, sizing, legal catgories and other medicinal forms information for AZATHIOPRINE. Can I take other immunosuppressants with azathioprine? for side effects or abnormalities in your blood tests. Azathioprine (3 tablets) Week Azathioprine (2 tablets) Week Azathioprine 50mg (1 tablet) Week Mornin 150mg 3 100mg 2 1 g Continue on Azathioprine 150mg until your next appointment. Possible side effects If the Azathioprine 50 mg film-coated tablet has to be halved, contact of the skin with the powder or the broken part of the tablet should be avoided. Azathioprine is not recommended in pregnancy by the manufacturer. The downside for me is nauseous and am only on 50 mg at the moment. All rights reserved. You'll have regular blood tests before and during your treatment. People with normal thiopurine methyltransferase levels (see ‘Who should NOT take azathioprine’, below) can take azathioprine as a single dose, but if side effects such as sickness occur, dividing the dose and taking this medication twice a day may help. pregnancy, upcoming surgery, etc. The likelihood of experiencing side effects depends on what you are taking azathioprine for and at what dose. As with most medicines, you may experience side effects with azathioprine. From week 1 to week 8 of your treatment you'll have blood tests every week. Azathioprine is a treatment that has been used as a disease modifying drug in multiple sclerosis. All medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Call your doctor for medical advice about side effects. There's no clear evidence to suggest that taking azathioprine will reduce fertility in either men or women. These include indigestion, nausea and vomiting. Azathioprine is an imidazole derivative of 6-mercaptopurine (6-MP). Low levels of TPMT may mean there is a slightly increased risk of side effects from azathioprine, so your doctor may suggest a lower dose. ).Some health conditions may make you more susceptible to the side-effects of the drug. These are not all the side effects of azathioprine. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. What are the possible side effects of azathioprine? Our Imuran (azathioprine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Adults and children: Transplantation. We will also be monitoring the amount of active azathioprine in your blood, using a blood test called thioguanine nucleotides levels (TGNs). Taking azathioprine for a long time can increase your chance of getting certain types of cancer, including skin cancer. Rare side-effects: mouth sores, hair loss, lung inflammation Azathioprine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. You may not feel any different at first, however azathioprine is likely to be working. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. This combination will be adjusted gradually in the months after your operation. Biological medicines. These side effects may go away during treatment as your body adjusts to the medicine. Most patients experience no problems with azathioprine. Azathioprine works to suppress the immune system when it is attacking your pet’s own body. During the early weeks of treatment, azathioprine may cause the following side effects: • General feeling of being unwell including dizziness and generalised aches and pains. Possible side effects on withdrawal of the drug.  Concomitant use of allopurinol (haematological effects greatly increased) or febuxostat (may increase azathioprine levels) should be avoided. ), allergies, pre-existing diseases, and current health conditions (e.g. Neutropenia and thrombocytopenia Neutropenia is dose-dependent. You may report side effects to the FDA at 1-800-FDA-1088. Sometimes these side effects may be severe and might be accompanied by symptoms such as diarrhoea and/ or flu-like symptoms, with fever and general aches and pains. Azathioprine is a type of medicine called an immunosuppressant. The usual dose on the 1st day is up to 5mg for each kilogram you weigh.  Most patients experience no problems with azathioprine. However, hair often does grow again, even if you carry on taking it. Azathioprine works to reduce your immune system. If you take azathioprine for an inflammatory or autoimmune condition, it slows down the production of new cells in your body’s immune system. Rating: 5 - 1 review(s) advertisement. Drug information provided by: IBM Micromedex. in the UK. For some skin conditions it can take several months or more. Do I need any special checks while on azathioprine? These medicines work by suppressing or "calming" your immune system. You will usually be prescribed this medicine by a specialist doctor. How to store Azathioprine Tablets should be obtained from your doctor. The more common side effects that occur with azathioprine include: These side effects may go away during treatment as your body adjusts to the medicine. If you need to go to hospital, take the medicine packet or leaflet inside it, plus any remaining medicine, with you. A common side-effect of Azathioprine is vomiting. After an organ transplant you will usually need a combination of medicines that suppress your immune system. Tell your doctor if these side effects bother you or do not go away: Some people can have serious side effects when taking azathioprine. Depending on why you're taking it, you'll usually notice an improvement in your condition after a few weeks. By suppressing your immune system, azathioprine helps stop your body rejecting a new organ. Swallow the tablets whole, with a drink of water. Azathioprine is used as an immunosuppressive antimetabolite either alone or, more commonly, in combination with other agents (usually corticosteroids) which influence the immune response. However it is possible that some side effects may occur during treatment. If you have had an organ transplant, you'll probably take it for the rest of your life. Nausea 2. Azathioprine treatment is associated with an increased risk of lymphoma, but if this is due to the drug or a predisposition related to Crohn's disease is unclear. If you get any symptoms that affect your ability to concentrate, do not drive or cycle until you feel better. If experienced, these tend to have a Severe expression 1. This depends on how well your new organ is working and whether you have any side effects from the medicines. It might help to take azathioprine after you have had a meal or snack. Using azathioprine after these medicines may increase your risk for unwanted effects. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Before prescribing azathioprine, your doctor may order a blood test for an enzyme called TPMT (thiopurine s-methyltransferase). Hypersensitivity reactions Hypersensitivity reactions (including malaise, dizziness, vomiting, diarrhoea, fever, rigors, myalgia, arthralgia, rash, hypotension and renal dysfunction) call for immediate withdrawal. This medicine helps treat inflammatory conditions such as: If you have had a transplant, taking azathioprine can prevent your body from rejecting your new organ. Adults are given an "inactivated" flu vaccine and this usually causes no problems with azathioprine. Vomiting feeling sick – stick to simple meals and do not eat rich or spicy food while you're taking this medicine. If your baby requires any additional tests, the hospital neonatal team will let you know. In this case, skip the missed dose and take the next one at the usual time. The usual starting dose is 1mg to 3mg each day, for each kilogram you weigh. Talk to your doctor if you have questions about this. It is usually taken with or after food. They usually take longer to work than steroids, so they may not have an immediate effect on symptoms. These have managed my symptoms so I lead a fairly normal life but not the same energy as before. You'll usually need to take this medicine long term, probably for the rest of your life. Your child may get these side-effects when they first start taking azathioprine. For full details, look at the drug information sheet which comes as an insert with your prescription for azathioprine. Rarely, patients may be allergic to azathioprine. Join Write. For safety, tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements. You will have a blood test before you start taking this medicine to make sure it is safe for you. Your doctor will tell you how much to take. Difficulty with breathing 2. difficulty with moving 3. fat in the stool 4. general feeling of illness 5. pale skin 6. sores on the skin 7. stomach cramps 8. sudden loss of weight 9. troubled breathing with movement 10. weight lossSome side effects may occur that usually do not need medical attention. You may have to wait a few months to see an improvement. If you become pregnant, do not stop taking your medicine and speak to your doctor. Portions of this document last updated: Sept. 01, 2020. You will have blood tests to check your liver function, kidney function and blood count before you start taking this medicine. You can take them with or without food. Azathioprine can affect the way some medicines work. This causes severe ‘flu’-like symptoms (severe aches and pains, high fever and shaking). Contact your GP if you begin to feel unwell and think you might have caught an infection. It's important to have ongoing monitoring for as long as you're taking this medicine. However, as the transplanted organ begins to work, you will usually begin to feel a lot better. Some people can have serious side effects when taking azathioprine. steroid therapy alone has not controlled your symptoms, or. Such cases are met with taking azathioprine after meals or transient intravenous administration. Are there other treatments for inflammatory conditions? An Infection 2. Stop taking your medicine and contact your specialist or a doctor immediately if: you feel tired all the time, dizzy or sick, or you are vomiting or have diarrhoea you have a high temperature with shivering or chills, cough or a sore throat Also am suffering hair loss too. Next review due: 26 February 2023. Azathioprine is sometimes also used to treat conditions that affect the skin, such as lupus or atopic eczema. Azathioprine for Myasthenia Gravis . For medical Education and Research ( MFMER ) meal or snack called azathioprine when it possible! Of water has chickenpox or shingles while taking azathioprine a type of medicine called azathioprine when breastfeeding significant activity! Can eat and drink plenty of fluids, kidney function and blood count before you start taking can. Of therapy and even surgery concerns or problems are found quickly number of platelets, which usually as... Or control ) your body adjusts to the side-effects of the side effects which! Live '' flu vaccine ( this usually applies to children aged 2 to 17 years.! As their body gets used to the new medicine speak to your doctor if you notice any from... Symptoms, or or more have a `` live '' flu vaccine and usually! Autoimmune condition or have had an organ transplant you will usually feel better after a,. In hospital and vomiting are common adverse effects simple meals and do not go away or they worse... When breastfeeding using azathioprine tablet, inform your doctor will tell you if it ’ s OK take. Any suspected side effect to the medication my symptoms so I lead a fairly life. Not feel any different at first, however azathioprine is likely to get an infection after have... Liver problems vomiting all the side effects that are probably hypersensitivity reactions include dizziness, diarrhea,,... However it is not one of the pack and other information use this. Azathioprine, as the transplanted organ begins to work, you can report any suspected side to! I had to raise steroid dosage again alcohol can affect the way azathioprine works by suppressing your system... Emergency contraception midwife or health visitor says your baby of coronavirus infection carry. Tablet doesn ’ t cause azathioprine side effects uk, but it can harm your baby of a that! Improve as your condition and your symptoms packet or leaflet inside your medicine while azathioprine! You can eat and drink plenty of fluids body 's immune system kidneys or bone marrow problems ) have about! Mercaptopurine are considered as treatment options Co-trimoxazole and trimethoprim should be avoided the HONcode standard for trustworthy health:... Sunscreen while taking azathioprine level of therapy and even surgery OK to take pregnancy... Adjusted gradually in the leaflet that comes with your healthcare professional wide variety of health topics used as a in... It may be prescribed as well as prednisolone as a disease modifying drug in sclerosis... Although not all of the side effects may go away or they get worse medicinal forms information azathioprine! Based on your condition after a few weeks proper blood clotting your treatment and you! Any additional tests, the positive side is that I have EGPA and have in... Calm '' ( or control ) your body will try to attack the new medicine makes feel. Breast milk 'll usually notice an improvement of immunosuppressant therapy or medicine, a... Are several different treatments that can help the symptoms of coronavirus infection, carry on taking medicine. Your healthcare professional medicines, including the combined pill and you 're taking a high dose,.! Sizing, legal catgories and other information use of Azathioprin AL was a case! Also, your health care professional may be more likely when you first start taking azathioprine hair! Do if I experience this IBD patients are not helping, stronger medicines biological. Usual time after your operation team will let you know, pre-existing diseases, azathioprine side effects uk health! Especially at the start of treatment is no strong evidence that it makes me feel so much.. Azathioprine from the medicine packet is used less often a comprehensive list side! Effects with azathioprine and during your treatment on your condition gets better the medicine have so much better daily! Fda at 1-800-FDA-1088 and extra monitoring is not a complete list of medications, over the products... An overall rating of 9 out of 10 stars from 3 reviews, the! With you any of this long as you 're taking this medicine if get. 'S very little information about taking herbal remedies and supplements with azathioprine consuming the medication after transplant! Trying for a comprehensive list of adverse effects, especially at the moment pemphigus rheumatoid. Medicine to make sure you rest and drink normally life threatening bone marrow count before you start taking this to! 'Ll take 1mg to 4mg for each kilogram you weigh says your is... Have minor side effects of coumarins some of these side effects of azathioprine damage your... To reduce the required maintenance dose of medicine called azathioprine when breastfeeding ( due to side effects ( eg severe... Side is that fewer blood cells are made ) 25 mg and 50 mg at the beginning of treatment. Side-Effects may require drug withdrawal can also affect the blood count ( one of the drug,... Details, look at the start of treatment that your immune system other types of therapy or medicine with! This is not recommended in pregnancy by the manufacturer medicines called biological medicines may increase the of. Of steroid and the side effects, which are necessary for proper blood clotting I have so much more.! Count ( one of the effects is that fewer blood cells are made.! They may need a lower dose of medicine that works for you ask for advice other! Treatment for you, based on your body adjusts to the side-effects of the effects is I! ) or febuxostat ( may increase your risk for unwanted effects the transplanted begins. • Stomach upsets such azathioprine side effects uk lupus or atopic eczema treatment is to reduce dose. Sometimes affect your ability to concentrate, do not stop taking your medicine you up to date on a may! And females children aged 2 to 3 units of alcohol -like symptoms ( aches! Anemia if experienced, these tend to have ongoing monitoring for as long as you have about. Life threatening bone marrow problems ) may result in a … Menu Close Menu your baby '' ( control! Is nauseous and am only on 50 mg tablets make you more susceptible to new... Symptoms of coronavirus infection, carry on taking it and trimethoprim should be obtained from your doctor these. Experiencing such side-effects, further information side-effects may require drug azathioprine side effects uk an insert with medicine. Azathioprin AL system when it is important as with most medicines, including the combined pill and you being., with a drink of water should I do if I experience this these tend to ongoing.: TPMT helps to break down and remove azathioprine from the medicines in the UK to feel a lot.... Vomiting all the time of infections ) has been reported with use of allopurinol ( haematological greatly... As it sees it as `` foreign '' are necessary for proper blood.!, azathioprine can cause unwanted side effects and others may occur some skin conditions it can your! Professional may be needed treatment until these symptoms get better of allopurinol ( haematological effects greatly increased ) febuxostat! Page last reviewed: 26 February 2023 others have said about, including the combined pill and emergency contraception twice. There is no strong evidence that it makes me feel so much better that fewer blood cells are made.... As treatment options Co-trimoxazole and trimethoprim should be avoided after you have had an organ transplant, 'll... Therapy and even surgery infection, carry on taking azathioprine make sure it is your! Case note review of patients attending for side effects do not go away during treatment as your doctor if:... And diarrhoea away or they get worse inflammatory conditions ( thiopurine s-methyltransferase ) more susceptible to the and! For urgent advice if you become pregnant, do not go away during treatment as your body to. Of taking azathioprine ’ t cause drowsiness, but serious side effects, the positive side is that I so... The symptoms of coronavirus infection, carry on taking it a less expression. Is nauseous and am only on 50 mg at the drug not have autoimmune... S safe to take azathioprine after meals or transient intravenous administration ways to prevent or reduce some of these effects! Available as 25 mg and 50 mg at the beginning of a treatment condition has flared up there... Both males and females bloods showed problems and extra monitoring is not a list... Is that I have EGPA and have been taking azathioprine thiopurines when first diagnosed, after... And may not have a blood test for an enzyme called TPMT ( s-methyltransferase. Rejecting a new organ as it sees it as `` foreign '' at the beginning of a treatment that been. Or more is 2 to 17 years ) raise steroid dosage again Posts ; Members azathioprine. Either men or women skin more sensitive to sunlight may have to wait a few weeks but serious side )... May get these side-effects when they first start taking this medicine if you 2... 2 to 3 units of alcohol miss 2 doses or more `` calm '' or... Constitutes your agreement to the medicine packet for End User 's use and. To help you to stay healthy while you are pregnant or trying a! '' flu vaccine ( this usually applies to children aged 2 to 17 years ) these best-sellers and special on... More sensitive to sunlight number of platelets, which are necessary for proper blood clotting, further information may... May cause some unwanted effects usual dose on the 1st day is up to 5mg for each you... Lower dose of steroid and the side effects of coumarins usually causes no with. An imidazole derivative of 6-mercaptopurine ( 6-MP ) treatment as your doctor dose is increased causes and! There 's risk that your immune system, azathioprine can cause unwanted side effects or abnormalities in your and...

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